Recombinant Bcl2 Monoclonal Antibody
Product Specifications
Background
BCL2 belongs to the Bcl-2 family. It suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. BCL2 regulates cell death by controlling the mitochondrial membrane permeability. It appears to function in a feedback loop system with caspases. BCL2 inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) .
Abbreviation
Bcl2
UniProt
P10415
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide of human Bcl-2
Target
Apoptosis regulator Bcl 2; Apoptosis regulator Bcl-2; Apoptosis regulator Bcl2; AW986256; B cell CLL/lymphoma 2; B cell leukemia/lymphoma 2; Bcl-2; Bcl2; BCL2; C430015F12Rik; D630044D05Rik; D830018M01Rik; Leukemia/lymphoma; B-cell;2; Oncogene B-cell leukemia 2; PPP1R50; Protein phosphatase 1; regulatory subunit 50
Clonality
Monoclonal
Clone
R03-9E1
Conjugation
Unconjugated
Applications
WB; IHC-P
Field of Research
Cancer; Cell Biology; Metabolism; Signal Transduction
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:500-1:1000; IHC 1:20-1:200
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
26kDa
Observed Molecular Weight
26kDa
Isotype
IgG
Available Sizes
Documents
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TA592127S 30 µL
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