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CD284 Polyclonal Antibody

Product Specifications

Background

TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS) . TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.

Abbreviation

CD284

UniProt

O00206, Q9QUK6, Q9QX05

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse TLR4.

Target

ARMD10; CD284; CD284 antigen; Homolog of Drosophila toll; hToll; TLR 4; TLR4; TLR4; TOLL; Toll like receptor 4; Toll-like receptor 4

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Cardiovascular; Immunology; Microbiology

Purification

Affinity purification

Concentration

0.9 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:500-1:2000

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

95kDa

Observed Molecular Weight

95kDa

Citation 01

https://www.sciencedirect.com/science/article/pii/S0024320521008626

Citation 02

https://academic.oup.com/jpp/article-abstract/73/4/473/6118677

Isotype

IgG

Available Sizes

Documents

Product Datasheet

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