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BMP2 Monoclonal Antibody

Product Specifications

Background

Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer, which binds to its receptor. There is also a 40-45 kDa form of BMP2, as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction.

Abbreviation

BMP2

UniProt

P12643, P21274, P49001

Host

Mouse

Reactivity

Rat

Immunogen

Recombinant protein corresponding to Mouse BMP2

Target

BDA2; BMP-2; BMP-2A; Bmp2; BMP2; BMP2A; Bone morphogenetic protein 2; Bone morphogenetic protein 2A

Clonality

Monoclonal

Clone

2H6D12

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Cardiovascular; Signal Transduction; Stem Cells

Purification

Affinity purification

Concentration

2.65 mg/mL

Dilution

IHC 1:200-1:800

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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