C-Kit Polyclonal Antibody

Product Specifications

Background

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor) . Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

Abbreviation

C-Kit

UniProt

P10721, P05532

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant protein corresponding to Mouse c-Kit

Target

C Kit; c-Kit; c-Kit Ligand; CD117; Kit; Kit Ligand; KIT oncogene; KIT proto oncogene receptor tyrosine kinase; KIT; Mast cell growth factor receptor; Mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; Proto oncogene c Kit; Proto oncogene tyrosine protein kinase Kit; Proto-oncogene c-Kit; SCF Receptor; SCFR; soluble KIT variant 1; Steel Factor Receptor; Stem cell factor receptor; tyrosine protein kinase Kit; Tyrosine-protein kinase Kit; v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog; v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

Field of Research

Cancer; Developmental Biology; Immunology; Neuroscience; Signal Transduction; Stem Cells; Tags and Cell Markers

Purification

Affinity purification

Concentration

3 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

110kDa

Observed Molecular Weight

145kDa

Citation 01

https://www.frontiersin.org/articles/10.3389/fphys.2022.828578/full?utm_source=dlvr.it&utm_medium=twitter

Citation 02

https://www.sciencedirect.com/science/article/pii/S0378874121001513

Isotype

IgG

Available Sizes

Documents

Product Datasheet

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