GCG Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
Abbreviation
GCG
UniProt
P55095, P06883
Host
Rabbit
Reactivity
Mouse; Rat
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Glucagon
Target
GCG; GLP 2; GLP1; GLP2; glucagon; GRPP; Glucagon like peptide 1; GRPP Oxyntomodulin; OXM; Proglucagon
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Metabolism; Developmental Biology; Signal Transduction; Stem Cells
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
21kDa
Observed Molecular Weight
25kDa
Citation 01
https://www.sciencedirect.com/science/article/pii/S0944711323000910
Isotype
IgG
Available Sizes
Documents
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