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GCG Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.

Abbreviation

GCG

UniProt

P55095, P06883

Host

Rabbit

Reactivity

Mouse; Rat

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Glucagon

Target

GCG; GLP 2; GLP1; GLP2; glucagon; GRPP; Glucagon like peptide 1; GRPP Oxyntomodulin; OXM; Proglucagon

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Cancer; Metabolism; Developmental Biology; Signal Transduction; Stem Cells

Purification

Affinity purification

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

21kDa

Observed Molecular Weight

25kDa

Citation 01

https://www.sciencedirect.com/science/article/pii/S0944711323000910

Isotype

IgG

Available Sizes

Curated Selection

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