PPARG Polyclonal Antibody

Product Specifications

Background

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

Abbreviation

PPARG

UniProt

P37231, P37238, O88275

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant protein corresponding to Mouse PPARγ

Target

CIMT1; GLM1; NR1C3; Nuclear receptor subfamily 1 group C member 3; OTTHUMP00000185032; OTTHUMP00000185036; Peroxisome proliferator activated nuclear receptor gamma variant 1; Peroxisome proliferator activated receptor gamma 1; Peroxisome Proliferator Activated Receptor gamma; Peroxisome proliferator-activated receptor gamma; PPAR gamma; PPAR-gamma; PPARG; PPARG; PPARG1; PPARG2; PPARgamma

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

Field of Research

Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Metabolism; Neuroscience; Stem Cells

Purification

Affinity purification

Concentration

0.58 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

58Da

Observed Molecular Weight

50-60kDa

Citation 01

https://www.sciencedirect.com/science/article/pii/S1388198120301694

Citation 02

https://www.sciencedirect.com/science/article/pii/S0898656818301724

Citation 03

https://www.sciencedirect.com/science/article/pii/S1098882317300783

Citation 04

https://www.sciencedirect.com/science/article/pii/S0006291X19316687

Citation 05

https://europepmc.org/article/med/31999897?javascript_support=no

Isotype

IgG

Available Sizes

Documents

Product Datasheet

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