CD163 Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Abbreviation
CD163
UniProt
Q86VB7, Q2VLH6
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein corresponding to Mouse CD163
Target
C163A; CD 163; CD163; CD163 antigen; CD163 molecule; Hemoglobin scavenger receptor; M130; M130 antigen precursor; Macrophage associated antigen; MM130; OTTHUMP00000238617; OTTHUMP00000238618; OTTHUMP00000238619; OTTHUMP00000238620; SCARI1; Scavenger receptor cysteine rich type 1 protein M130; sCD163; Soluble CD163
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Cardiovascular; Immunology
Purification
Affinity purification
Concentration
360 μg/mL
Dilution
WB 1:1000-1:2000
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
125kDa
Observed Molecular Weight
145kDa
Citation 01
https://link.springer.com/article/10.1186/s12929-022-00855-6
Citation 02
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746334/
Isotype
IgG
Available Sizes
Documents
Curated Selection
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