COL2A1 Monoclonal Antibody
Product Specifications
Background
This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.
Abbreviation
COL2A1
UniProt
P28481
Host
Mouse
Reactivity
Mouse; Rat
Immunogen
Recombinant protein corresponding to Mouse collagen II
Target
Alpha 1 type II collagen; Alpha-1 type II collagen; AOM; Cartilage collagen; Chondrocalcin; CO2A1; COL11A3; Col2a1; Collagen II alpha 1 polypeptide; SEDC
Clonality
Monoclonal
Clone
2F12D3
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Signal Transduction; Stem Cells
Purification
Affinity purification
Concentration
2.6 mg/mL
Dilution
IHC 1:300-1:1000
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Documents
Curated Selection
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