ERK1/2 Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Abbreviation
ERK1/2
UniProt
P28482, P27361, P63085, P63086, P21708, Q63844
Host
Mouse
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein corresponding to Mouse ERK2
Target
MAPK3; ERK1; PRKM3; Mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase
Clonality
Monoclonal
Clone
4H6A4
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Neuroscience; Signal Transduction; Stem Cells
Purification
Affinity purification
Concentration
3.2 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
42/44kDa
Observed Molecular Weight
42/44kDa
Citation 01
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523073/
Isotype
IgG
Available Sizes
Documents
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