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GABAA Receptor alpha1 Polyclonal Antibody

Product Specifications

Background

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene

Abbreviation

GABAA Receptor alpha1

UniProt

P14867, P62813, P62812

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

KLH conjugated Synthetic peptide corresponding to mouse GABA A Receptor alpha 1

Target

ECA4; EIEE19; EJM; EJM5; Gaba receptor alpha 1 polypeptide; GABA (A) receptor; GABA (A) receptor subunit alpha 1; GABA (A) receptor subunit alpha-1; GABA (A) receptor; alpha 1; GABRA 1; GABRA1; Gamma aminobutyric acid (GABA) A receptor alpha 1; Gamma aminobutyric acid A receptor alpha 1; Gamma aminobutyric acid receptor subunit alpha 1; Gamma aminobutyric acid type A receptor alpha1 subunit; Gamma-aminobutyric acid receptor subunit alpha-1; GBRA1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Cancer; Neuroscience

Purification

Affinity purification

Concentration

0.73 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

52kDa

Observed Molecular Weight

52kDa

Isotype

IgG

Available Sizes

Frequently Asked Questions

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