BAG2 Polyclonal Antibody
Product Specifications
Background
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Abbreviation
BAG2
UniProt
Q91YN9
Host
Rabbit
Reactivity
Rat
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Bag2
Target
BAG 2; BAG family molecular chaperone regulator 2; BAG-2; BAG-family molecular chaperone regulator-2; Bag2; BAG2; BCL 2 associated athanogene 2; Bcl-2-associated athanogene 2; BCL2 associated athanogene 2; BCL2-associated athanogene 2; dJ417I1.2 (BAG family molecular chaperone regulator 2) ; dJ417I1.2; KIAA0576; MGC149462; OTTHUMP00000016668
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cell Biology; Signal Transduction; Cancer; Metabolism
Purification
Affinity purification
Concentration
0.89 mg/mL
Dilution
IHC 1:200-1:800
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/eumqms
Product MSDS
https://789.bio/eb/nzb54G
Isotype
IgG
Available Sizes
Curated Selection
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