LDLR Polyclonal Antibody
Product Specifications
Background
LDLR (low density lipoprotein receptor) is a member of the LDL receptor gene family and is involved in receptor-mediated endocytosis of specific ligands. The LDLR is a cell surface glycoprotein that scavenges LDL from the blood and regulates plasma LDL cholesterol. The cytoplasmic domain of the LDL receptor is necessary for the receptor to cluster in coated pits, which promotes the rapid endocytosis of bound LDL. The protein is highly glycosylated through N- and O-linkages and thus migrates at 100 to 160 kDa bands on SDS-PAGE.
Abbreviation
LDLR
UniProt
P01130, P35951, P35952
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
KLH conjugated Synthetic peptide corresponding to LDL Receptor
Target
FH; FHC; LDL R; LDL receptor; LDLCQ2; Ldlr; LDLR; Low Density Lipoprotein Receptor; Low density lipoprotein receptor class A domain containing protein 3; Low density lipoprotein receptor familial hypercholesterolemia; Low-density lipoprotein receptor
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cardiovascular; Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
IHC 1:200-1:1000
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Citation 01
https://static.frontiersin.org/articles/10.3389/fonc.2022.903033/full
Isotype
IgG
Available Sizes
Documents
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