CD284 Monoclonal Antibody
Product Specifications
Background
TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS) . TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
Abbreviation
CD284
UniProt
Q9QUK6, Q9QX05
Host
Mouse
Reactivity
Mouse; Rat
Immunogen
Recombinant protein corresponding to Mouse TLR4
Target
ARMD10; CD284; CD284 antigen; Homolog of Drosophila toll; hToll; TLR 4; TLR4; TLR4; TOLL; Toll like receptor 4; Toll-like receptor 4
Clonality
Monoclonal
Clone
2E12C8
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cardiovascular; Immunology; Microbiology
Purification
Affinity purification
Concentration
1.8 mg/mL
Dilution
IHC 1:200-1:800
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
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