NOX4 Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS) . The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
Abbreviation
NOX4
UniProt
Q9NPH5, Q9JHI8, Q924V1
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse NOX4
Target
Kidney oxidase 1; Kidney oxidase-1; Kidney superoxide producing NADPH oxidase; Kidney superoxide-producing NADPH oxidase; KOX 1; KOX; Kox-1; KOX1; NADPH; NADPH oxidase 4; Nox4; NOX4; Renal NAD (P) H oxidase; Renal NAD (P) H-oxidase; RENOX
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cell Biology; Cardiovascular; Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
0.9 mg/mL
Dilution
WB 1:1000-1:2000; IHC 1:400-1:1000
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
70kDa
Observed Molecular Weight
70kDa
Isotype
IgG
Available Sizes
Documents
More Discoveries
Explore Other Products
Browse additional items from our catalog
