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MAP2K1 Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

Abbreviation

MAP2K1

UniProt

Q02750, Q01986, P31938

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse MEK1

Target

Dual specificity mitogen activated protein kinase kinase 1; Dual specificity mitogen-activated protein kinase kinase 1; ERK activator kinase 1; MAP kinase kinase 1; MAP kinase/Erk kinase 1; MAP2K1; MAPK/ERK kinase 1; MAPKK 1; MAPKK1; MEK 1; Mek1; MEKK1; Mitogen activated protein kinase kinase 1; MKK 1; MKK1; MP2K1; PRKMK1; Protein kinase mitogen activated kinase 1 (MAP kinase kinase 1) ; Protein kinase mitogen activated; kinase 1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Cancer; Signal Transduction

Purification

Affinity purification

Concentration

240 μg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

45kDa

Observed Molecular Weight

45kDa

Isotype

IgG

Available Sizes

Curated Selection

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