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C-Fos Monoclonal Antibody

Product Specifications

Background

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.

Abbreviation

C-Fos

UniProt

P01100, P01101, P12841

Host

Mouse

Reactivity

Human; Mouse; Rat

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse c-FOS

Target

Activator protein 1; AP 1; C FOS; Cellular oncogene c fos; Cellular oncogene fos; FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS) ; FBJ murine osteosarcoma viral oncogene homolog; FBJ murine osteosarcoma viral v fos oncogene homolog; FBJ Osteosarcoma Virus; FOS; FOS protein; FOS; G0 G1 switch regulatory protein 7; G0/G1 switch regulatory protein 7; G0S7; Oncogene FOS; p55; proto oncogene c Fos; Proto oncogene protein c fos; Proto-oncogene c-Fos; v fos FBJ murine osteosarcoma viral oncogene homolog

Clonality

Monoclonal

Clone

4B4F11

Conjugation

Unconjugated

Applications

WB; IHC; IF

Field of Research

Cancer; Epigenetics and Nuclear Signaling; Neuroscience

Purification

Affinity purification

Concentration

0.97 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:500-1:2000; IF 1:200-1:1000

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

62kDa

Observed Molecular Weight

62kDa

Citation 01

https://www.sciencedirect.com/science/article/pii/S0024320519305582

Isotype

IgG

Available Sizes

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