C-Fos Monoclonal Antibody
Product Specifications
Background
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Abbreviation
C-Fos
UniProt
P01100, P01101, P12841
Host
Mouse
Reactivity
Human; Mouse; Rat
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse c-FOS
Target
Activator protein 1; AP 1; C FOS; Cellular oncogene c fos; Cellular oncogene fos; FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS) ; FBJ murine osteosarcoma viral oncogene homolog; FBJ murine osteosarcoma viral v fos oncogene homolog; FBJ Osteosarcoma Virus; FOS; FOS protein; FOS; G0 G1 switch regulatory protein 7; G0/G1 switch regulatory protein 7; G0S7; Oncogene FOS; p55; proto oncogene c Fos; Proto oncogene protein c fos; Proto-oncogene c-Fos; v fos FBJ murine osteosarcoma viral oncogene homolog
Clonality
Monoclonal
Clone
4B4F11
Conjugation
Unconjugated
Applications
WB; IHC; IF
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Neuroscience
Purification
Affinity purification
Concentration
0.97 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:500-1:2000; IF 1:200-1:1000
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
62kDa
Observed Molecular Weight
62kDa
Citation 01
https://www.sciencedirect.com/science/article/pii/S0024320519305582
Isotype
IgG
Available Sizes
Documents
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