CDC25A Polyclonal Antibody
Product Specifications
Background
CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.
Abbreviation
CDC25A
UniProt
P30304, P48965, P48964
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Cdc25A
Target
Cdc 25a; CDC25A; CDC25A2; CDC25A2 CAG isoform; Cell division cycle 25 homolog A (S. pombe) ; Cell division cycle 25A; Cell division cycle 25A isoform a; Cell division cycle 25A isoform b; D9Ertd393e; Dual specificity phosphatase Cdc25A; M phase inducer phosphatase 1; M-phase inducer phosphatase 1; MGC115549; MPIP1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cell Biology; Epigenetics and Nuclear Signaling
Purification
Affinity purification
Concentration
0.96 mg/mL
Dilution
WB 1:500-1:1000; IHC 1:500-1:1000
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/0h9dl8
Product MSDS
https://789.bio/eb/j9S0S4
Calculated Molecular Weight
65-70kDa
Observed Molecular Weight
70kDa
Isotype
IgG
Available Sizes
Curated Selection
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