TGF β Receptor I Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS) . Multiple transcript variants encoding different isoforms have been found for this gene.
Abbreviation
TGF β Receptor I
UniProt
P36897, Q64729, P80204
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse TGFβR1
Target
AAT 5; AAT5; Activin A receptor type II like kinase 53kDa; Activin A receptor type II like kinase;53kD; Activin A receptor type II like protein kinase of 53kD; activin A receptor type II-like kinase;53kDa; activin A receptor type II-like protein kinase of 53kD; Activin receptor like kinase 5; Activin receptor-like kinase 5; ACVRLK 4; ACVRLK4; ALK 5; ALK-5; ALK5; LDS1A; LDS2A; MSSE; Serine/threonine protein kinase receptor R4; Serine/threonine-protein kinase receptor R4; SKR 4; SKR4; TbetaR I; TbetaR-I; TGF beta receptor type 1; TGF beta receptor type I; TGF beta type I receptor; TGF-beta receptor type I; TGF-beta receptor type-1; TGF-beta type I receptor; TGFBR 1; TGFBR1; TGFBR1 protein; TGFR 1; TGFR-1; TGFR1; TGFR1; Transforming growth factor beta receptor 1; Transforming growth factor beta receptor I (activin A receptor type II like kinase;53kD) ; Transforming growth factor beta receptor I; transforming growth factor; beta receptor 1; transforming growth factor; beta receptor I (activin A receptor type II-like kinase;53kD) ; Transforming growth factor-beta receptor type I
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Cardiovascular; Metabolism; Signal Transduction; Stem Cells
Purification
Affinity purification
Concentration
0.9 mg/mL
Dilution
WB 1:500-1:1000
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/uailvh
Product MSDS
https://789.bio/eb/40Cm9C
Calculated Molecular Weight
56kDa
Observed Molecular Weight
56kDa
Citation 01
https://www.nature.com/articles/s41467-022-35262-w
Isotype
IgG
Available Sizes
Curated Selection
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