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TGF β Receptor I Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS) . Multiple transcript variants encoding different isoforms have been found for this gene.

Abbreviation

TGF β Receptor I

UniProt

P36897, Q64729, P80204

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse TGFβR1

Target

AAT 5; AAT5; Activin A receptor type II like kinase 53kDa; Activin A receptor type II like kinase;53kD; Activin A receptor type II like protein kinase of 53kD; activin A receptor type II-like kinase;53kDa; activin A receptor type II-like protein kinase of 53kD; Activin receptor like kinase 5; Activin receptor-like kinase 5; ACVRLK 4; ACVRLK4; ALK 5; ALK-5; ALK5; LDS1A; LDS2A; MSSE; Serine/threonine protein kinase receptor R4; Serine/threonine-protein kinase receptor R4; SKR 4; SKR4; TbetaR I; TbetaR-I; TGF beta receptor type 1; TGF beta receptor type I; TGF beta type I receptor; TGF-beta receptor type I; TGF-beta receptor type-1; TGF-beta type I receptor; TGFBR 1; TGFBR1; TGFBR1 protein; TGFR 1; TGFR-1; TGFR1; TGFR1; Transforming growth factor beta receptor 1; Transforming growth factor beta receptor I (activin A receptor type II like kinase;53kD) ; Transforming growth factor beta receptor I; transforming growth factor; beta receptor 1; transforming growth factor; beta receptor I (activin A receptor type II-like kinase;53kD) ; Transforming growth factor-beta receptor type I

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Cancer; Cardiovascular; Metabolism; Signal Transduction; Stem Cells

Purification

Affinity purification

Concentration

0.9 mg/mL

Dilution

WB 1:500-1:1000

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

56kDa

Observed Molecular Weight

56kDa

Citation 01

https://www.nature.com/articles/s41467-022-35262-w

Isotype

IgG

Available Sizes

Curated Selection

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