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TLR9 Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.

Abbreviation

TLR9

UniProt

Q9EQU3, Q9NR96

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse TLR9

Target

CD289; TLR 9; TLR9; Toll like receptor 9; Toll like receptor 9 isoform A precursor; Toll like receptor 9 isoform B; Toll-like receptor 9

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Immunology; Signal Transduction

Purification

Affinity purification

Concentration

1.5 mg/mL

Dilution

IHC 1:100-1:500

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

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