PGR Polyclonal Antibody
Product Specifications
Background
PGR, also named as NR3C3 and PR, belongs to the nuclear hormone receptor family and NR3 subfamily. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. The ER and PR status has been used as a predictor of breast carcinoma responsiveness to endocrine therapy and as a prognostic indicator for early recurrence.
Abbreviation
PGR
UniProt
P06401, Q00175, Q63449
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Progesterone receptor
Target
NR3C3; Nuclear receptor subfamily 3 group C member 3; PGR; PR; PRA; PRB; PRGR; Progesterone receptor; Progestin receptor form A; Progestin receptor form B
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Neuroscience; Signal Transduction
Purification
Affinity purification
Concentration
1.32 mg/mL
Dilution
IHC 1:200-1:800
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Documents
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