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HER2/neu (654-662) GP2

Product Specifications

UNSPSC Description

HER2/neu (654-662) GP2 is a nine amino acid peptide derived from the human epidermal growth factor receptor 2 (HER2/nue, 654–662), induces HLA-A2-restricted cytotoxic T lymphocytes (CTL) reactive to various epithelial cancers[1][2].

Target Antigen

EGFR

Type

Peptides

Related Pathways

JAK/STAT Signaling;Protein Tyrosine Kinase/RTK

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/her2-neu-654-662-gp2.html

Purity

98.04

Solubility

H2O : < 0.1 mg/mL (ultrasonic)

Smiles

CC(C)C[C@@H](C(O)=O)NC([C@H]([C@@H](C)CC)NC(CNC([C@H](C(C)C)NC([C@H](C(C)C)NC([C@H](C)NC([C@H](CO)NC([C@H]([C@@H](C)CC)NC([C@H]([C@@H](C)CC)N)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Weight

884.11

References & Citations

[1]Sun Y, et al. Observing the temperature dependent transition of the GP2 peptide using terahertz spectroscopy. PLoS One. 2012;7(11):e50306.|[2]Tanaka Y, et al. Modification of the HER2/NEU-derived tumor antigen GP2 improves induction of GP2-reactive cytotoxic T lymphocytes. Int J Cancer. 2001 Nov;94(4):540-4.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P1855/HER2-neu-654-662-GP2-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P1855/HER2-neu-654-662-GP2-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

160790-21-6

Available Sizes

Curated Selection

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