HER2/neu (654-662) GP2
Product Specifications
UNSPSC Description
HER2/neu (654-662) GP2 is a nine amino acid peptide derived from the human epidermal growth factor receptor 2 (HER2/nue, 654–662), induces HLA-A2-restricted cytotoxic T lymphocytes (CTL) reactive to various epithelial cancers[1][2].
Target Antigen
EGFR
Type
Peptides
Related Pathways
JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/her2-neu-654-662-gp2.html
Purity
98.04
Solubility
H2O : < 0.1 mg/mL (ultrasonic)
Smiles
CC(C)C[C@@H](C(O)=O)NC([C@H]([C@@H](C)CC)NC(CNC([C@H](C(C)C)NC([C@H](C(C)C)NC([C@H](C)NC([C@H](CO)NC([C@H]([C@@H](C)CC)NC([C@H]([C@@H](C)CC)N)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Weight
884.11
References & Citations
[1]Sun Y, et al. Observing the temperature dependent transition of the GP2 peptide using terahertz spectroscopy. PLoS One. 2012;7(11):e50306.|[2]Tanaka Y, et al. Modification of the HER2/NEU-derived tumor antigen GP2 improves induction of GP2-reactive cytotoxic T lymphocytes. Int J Cancer. 2001 Nov;94(4):540-4.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P1855/HER2-neu-654-662-GP2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P1855/HER2-neu-654-662-GP2-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
160790-21-6
Available Sizes
Curated Selection
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