HER2/neu (654-662) GP2

HER2/neu (654-662) GP2 is a nine amino acid peptide derived from the human epidermal growth factor receptor 2 (HER2/nue, 654–662), induces HLA-A2-restricted cytotoxic T lymphocytes (CTL) reactive to various epithelial cancers[1][2].

Product Specifications

CAS Number

[160790-21-6]

UNSPSC

12352209

Target

EGFR

Type

Peptides

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/her2-neu-654-662-gp2.html

Purity

98.26

Solubility

H2O : < 0.1 mg/mL (ultrasonic)

Smiles

CC(C)C[C@@H](C(O)=O)NC([C@H]([C@@H](C)CC)NC(CNC([C@H](C(C)C)NC([C@H](C(C)C)NC([C@H](C)NC([C@H](CO)NC([C@H]([C@@H](C)CC)NC([C@H]([C@@H](C)CC)N)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C42H77N9O11

Molecular Weight

884.11

References & Citations

[1]Sun Y, et al. Observing the temperature dependent transition of the GP2 peptide using terahertz spectroscopy. PLoS One. 2012;7 (11) :e50306.|[2]Tanaka Y, et al. Modification of the HER2/NEU-derived tumor antigen GP2 improves induction of GP2-reactive cytotoxic T lymphocytes. Int J Cancer. 2001 Nov;94 (4) :540-4.