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Cyclin B1 Polyclonal Antibody

Product Specifications

Background

G2/mitotic-specific cyclin-B1 is a protein that in humans is encoded by the CCNB1 gene. The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34 (cdc2) to form the maturation-promoting factor (MPF) . Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.

Abbreviation

Cyclin B1

UniProt

P14635, P24860, P30277

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Cyclin B1

Target

CCNB 1; CCNB; ccnb1; CCNB1; Cyclin B1; G2 mitotic specific cyclin B1; G2/mitotic-specific cyclin-B1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC; IF

Field of Research

Cancer; Cell Biology; Epigenetics and Nuclear Signaling

Purification

Affinity purification

Concentration

270 μg/mL

Dilution

WB 1:500-1:2000; IHC 1:300-1:500; IF 1:100-1:300

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

55kDa

Observed Molecular Weight

55kDa

Citation 01

https://www.mdpi.com/1858600

Citation 02

https://www.mdpi.com/1574002

Citation 03

https://www.mdpi.com/1147980

Citation 04

https://www.mdpi.com/1420-3049/24/1/121

Isotype

IgG

Available Sizes

Frequently Asked Questions

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