BMP2 Polyclonal Antibody
Product Specifications
Background
Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer, which binds to its receptor. There is also a 40-45 kDa form of BMP2, as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction.
Abbreviation
BMP2
UniProt
P12643, P21274, P49001
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse BMP2
Target
BDA2; BMP-2; BMP-2A; Bmp2; BMP2; BMP2A; Bone morphogenetic protein 2; Bone morphogenetic protein 2A
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cardiovascular; Signal Transduction; Stem Cells
Purification
Affinity purification
Concentration
2.4 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:200-1:800
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
45kDa
Observed Molecular Weight
45kDa
Citation 01
https://www.hindawi.com/journals/bmri/2018/3874131/abs/
Isotype
IgG
Available Sizes
Documents
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