PTEN Polyclonal Antibody

Product Specifications

Background

PTEN (also designated MMAC1), products of tumor suppressor genes, are found deleted in most human gliomas. The PTEN genes are also mutated in many other tumors, such as brain, breast, kidney and prostate cancers. PTEN is a protein tyrosine phosphatase that may terminate the signaling transduction pathways mediated by PI 3-kinase/Akt. PTEN has an apparent molecular weight of 55 kDa and it is located in the cytosol.

Abbreviation

PTEN

UniProt

P60484, O08586

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse PTEN

Target

10q23del; BZS; DEC; GLM2; MGC11227; MHAM; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; Phosphatase and tensin like protein; Phosphatidylinositol 3;4;5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; Pten; PTEN; PTEN1; TEP1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Metabolism; Signal Transduction

Purification

Affinity purification

Concentration

480 μg/mL

Dilution

IHC 1:100-1:500

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

TA808244AM 100 µL

C4orf36 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3G7]

Ask

View Details