NOS1 Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.
Abbreviation
NOS1
UniProt
P29475, P29476, Q9Z0J4
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse nNOS
Target
2310005C01Rik; BNOS; Constitutive NOS; EC 1.14.13.39; IHPS 1; IHPS1; N-NOS; NC-NOS; neuronal Nitric Oxide Synthase; Neuronal NOS; Nitric oxide synthase; neuronal; included; Nitric oxide synthase 1 (neuronal) ; Nitric oxide synthase 1; Nitric oxide synthase; brain; Nitric oxide synthase; penile neuronal; included; NNOS; NO; NOS 1; NOS; NOS type I; NOS-I; NOS1; NOS1; Peptidyl-cysteine S-nitrosylase NOS1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Metabolism; Neuroscience
Purification
Affinity purification
Concentration
350 μg/mL
Dilution
WB 1:500-1:2000; IHC 1:300-1:800
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
161kDa
Observed Molecular Weight
161kDa
Citation 01
https://www.mdpi.com/1587758
Isotype
IgG
Available Sizes
Curated Selection
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