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NOS1 Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.

Abbreviation

NOS1

UniProt

P29475, P29476, Q9Z0J4

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse nNOS

Target

2310005C01Rik; BNOS; Constitutive NOS; EC 1.14.13.39; IHPS 1; IHPS1; N-NOS; NC-NOS; neuronal Nitric Oxide Synthase; Neuronal NOS; Nitric oxide synthase; neuronal; included; Nitric oxide synthase 1 (neuronal) ; Nitric oxide synthase 1; Nitric oxide synthase; brain; Nitric oxide synthase; penile neuronal; included; NNOS; NO; NOS 1; NOS; NOS type I; NOS-I; NOS1; NOS1; Peptidyl-cysteine S-nitrosylase NOS1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Metabolism; Neuroscience

Purification

Affinity purification

Concentration

350 μg/mL

Dilution

WB 1:500-1:2000; IHC 1:300-1:800

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

161kDa

Observed Molecular Weight

161kDa

Citation 01

https://www.mdpi.com/1587758

Isotype

IgG

Available Sizes

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