N-cadherin Polyclonal Antibody

Product Specifications

Background

Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. N-cadherin (neural cadherin), also known as CDH2 (cadherin 2), is a classical member of the cadherin superfamily which also include E-, P-, R-, and B-cadherins. Expression of N-cadherin has been reported on various cell types including neurons, endothelial cells and cardiac myocytes . N-cadherin has functions in early brain morphogenesis, synaptogenesis and synaptic plasticity .

Abbreviation

N-cadherin

UniProt

P19022, P15116, Q9Z1Y3

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse N-cadherin

Target

CADH2; Cadherin 2; Cadherin 2 N cadherin neuronal; Cadherin 2 type 1; Cadherin 2 type 1 N cadherin neuronal; Cadherin 2; type 1; N-cadherin (neuronal) ; Cadherin-2; Cadherin2; Calcium dependent adhesion protein neuronal; CD325; CD325 antigen; CDH2; CDHN; CDw325; CDw325 antigen; N cadherin 1; N-cadherin; NCAD; Neural cadherin; OTTHUMP00000066304; OTTHUMP00000067378

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Signal Transduction; Stem Cells

Purification

Affinity purification

Concentration

200 μg/mL

Dilution

WB 1:500-1:2000; IHC 1:300-1:800

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

100/120/140kDa

Observed Molecular Weight

120kDa

Citation 01

https://www.sciencedirect.com/science/article/pii/S1385894721041012

Citation 02

https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-021-01198-4

Citation 03

https://cellandbioscience.biomedcentral.com/articles/10.1186/s13578-023-00963-2

Citation 04

https://www.mdpi.com/2055064

Citation 05

https://www.mdpi.com/1660-3397/20/10/595

Citation 06

https://www.ncbi.nlm.nih.gov/pmc/articles/pmc8187004/

Citation 07

https://portlandpress.com/biochemj/article-abstract/doi/10.1042/BCJ20210830/231374

Citation 08

https://onlinelibrary.wiley.com/doi/abs/10.1002/mc.23264

Citation 09

https://www.ncbi.nlm.nih.gov/pmc/articles/pmc8607078/

Isotype

IgG

Available Sizes

Curated Selection

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