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CD54 Polyclonal Antibody

Product Specifications

Background

ICAM-1 (CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues . ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin . It is a ligand for LFA-1 and Mac-1, serves as a receptor for rhinovirus, and is one of several receptors used by Plasmodium falciparum .

Abbreviation

CD54

UniProt

P05362, Q00238, P13597

Host

Rabbit

Reactivity

Mouse; Rat

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse ICAM-1

Target

Antigen identified by monoclonal BB2; BB 2; BB2; CD 54; CD_antigen=CD54; CD54; Cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM 1; ICAM-1; ICAM1; ICAM1; intercellular adhesion molecule 1 (CD54) ; human rhinovirus receptor; Intercellular adhesion molecule 1; Major group rhinovirus receptor; MALA 2; MALA2; MyD 10; MyD10; P3.58; Surface antigen of activated B cells; BB2

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC; IF

Field of Research

Cancer; Cardiovascular; Immunology; Stem Cells

Purification

Affinity purification

Concentration

0.84 mg/mL

Dilution

WB 1:1000-1:3000; IHC 1:500-1:1000; IF 1:200-1:800

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

58kDa

Observed Molecular Weight

58kDa

Citation 01

https://www.ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.122.058794

Citation 02

https://pubs.acs.org/doi/abs/10.1021/acsami.9b22214

Isotype

IgG

Available Sizes

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