CD54 Polyclonal Antibody
Product Specifications
Background
ICAM-1 (CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues . ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin . It is a ligand for LFA-1 and Mac-1, serves as a receptor for rhinovirus, and is one of several receptors used by Plasmodium falciparum .
Abbreviation
CD54
UniProt
P05362, Q00238, P13597
Host
Rabbit
Reactivity
Mouse; Rat
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse ICAM-1
Target
Antigen identified by monoclonal BB2; BB 2; BB2; CD 54; CD_antigen=CD54; CD54; Cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM 1; ICAM-1; ICAM1; ICAM1; intercellular adhesion molecule 1 (CD54) ; human rhinovirus receptor; Intercellular adhesion molecule 1; Major group rhinovirus receptor; MALA 2; MALA2; MyD 10; MyD10; P3.58; Surface antigen of activated B cells; BB2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC; IF
Field of Research
Cancer; Cardiovascular; Immunology; Stem Cells
Purification
Affinity purification
Concentration
0.84 mg/mL
Dilution
WB 1:1000-1:3000; IHC 1:500-1:1000; IF 1:200-1:800
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
58kDa
Observed Molecular Weight
58kDa
Citation 01
https://www.ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.122.058794
Citation 02
https://pubs.acs.org/doi/abs/10.1021/acsami.9b22214
Isotype
IgG
Available Sizes
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