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GSK3 beta Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease.

Abbreviation

GSK3 beta

UniProt

P49841, Q9WV60, P18266

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse GSK3β

Target

Glycogen Synthase Kinase 3 Beta; Glycogen synthase kinase-3 beta; GSK 3 beta; GSK-3 beta; GSK3B; GSK3B; GSK3beta isoform; Serine/threonine-protein kinase GSK3B

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC; IF

Field of Research

Cancer; Cardiovascular; Metabolism; Neuroscience; Signal Transduction; Stem Cells

Purification

Affinity purification

Concentration

2 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:300-1:800; IF 1:200-1:500

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/deqpx5

Product MSDS

https://789.bio/eb/yTGq1S

Calculated Molecular Weight

47kDa

Observed Molecular Weight

47kDa

Citation 01

https://www.sciencedirect.com/science/article/pii/S0300483X22001044

Isotype

IgG

Available Sizes

Curated Selection

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