GSK3 beta Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease.
Abbreviation
GSK3 beta
UniProt
P49841, Q9WV60, P18266
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse GSK3β
Target
Glycogen Synthase Kinase 3 Beta; Glycogen synthase kinase-3 beta; GSK 3 beta; GSK-3 beta; GSK3B; GSK3B; GSK3beta isoform; Serine/threonine-protein kinase GSK3B
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC; IF
Field of Research
Cancer; Cardiovascular; Metabolism; Neuroscience; Signal Transduction; Stem Cells
Purification
Affinity purification
Concentration
2 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:300-1:800; IF 1:200-1:500
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
47kDa
Observed Molecular Weight
47kDa
Citation 01
https://www.sciencedirect.com/science/article/pii/S0300483X22001044
Isotype
IgG
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