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ITGAX Polyclonal Antibody

Product Specifications

Background

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits. CD11c/Integrin alpha X is a type I transmembrane protein present on a variety of cells, including monocytes/macrophages, granulocytes, NK cells and dendritic cells. Integrin alpha X/beta 2 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis.

Abbreviation

ITGAX

UniProt

P20702, Q9QXH4

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse CD11c

Target

95 alpha chain;95; CD 11c; CD11 antigen like family member C; CD11 antigen-like family member C; CD11c; CD11c antigen; Complement component 3 receptor 4 subunit; CR4; Integrin alpha X; Integrin alpha X chain; Integrin alpha-X; Integrin aX; Integrin subunit alpha X; integrin; alpha X (antigen CD11C (p150) ; alpha polypeptide) ; integrin; alpha X (complement component 3 receptor 4 subunit; ITAX; ITGAX; LEU M5 alpha subunit; Leu M5; Leukocyte adhesion glycoprotein p150 95 alpha chain; Leukocyte adhesion glycoprotein p150; Leukocyte adhesion receptor p150 95; Leukocyte adhesion receptor p150; Leukocyte surface antigen p150 95 alpha subunit; Leukocyte surface antigen p150 alpha subunit; Myeloid membrane antigen alpha subunit; p150 95 integrin alpha chain; p150; p150/95; SLEB6

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC; IF

Field of Research

Cancer; Immunology; Signal Transduction; Stem Cells

Purification

Affinity purification

Concentration

0.98 mg/mL

Dilution

WB 1:500-1:1000; IHC 1:100-1:300; IF 1:100-1:300

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

120-150kDa

Observed Molecular Weight

150kDa

Citation 01

https://www.nature.com/articles/s41419-019-1796-6

Citation 02

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226278/

Isotype

IgG

Available Sizes

Curated Selection

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