Catenin beta Polyclonal Antibody
Product Specifications
Background
CTNNB1, also known as β-Catenin, is an evolutionarily conserved, multifunctional intracellular protein. CTNNB1 was originally identified in cell adherens junctions (Ajs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the Ajs, CTNNB1 is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. Deregulation of CTNNB1 activity is associated with multiple diseases including cancers. .
Abbreviation
Catenin beta
UniProt
P35222, Q02248, Q9WU82
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse β-catenin
Target
Beta catenin; Beta-catenin; Cadherin associated protein; Catenin (cadherin associated protein) ; beta 1;88kDa; Catenin beta 1; Catenin beta-1; CATNB; CHBCAT; CTNB1; CTNNB; CTNNB1; DKFZp686D02253; FLJ25606; FLJ37923; OTTHUMP00000162082; OTTHUMP00000165222; OTTHUMP00000165223; OTTHUMP00000209288; OTTHUMP00000209289
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC; IF
Field of Research
Cancer; Cardiovascular; Neuroscience; Signal Transduction; Stem Cells
Purification
Affinity purification
Concentration
0.97 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:300-1:1000; IF 1:200-1:800
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
92kDa
Observed Molecular Weight
92kDa
Citation 01
https://academic.oup.com/bbb/article-abstract/85/11/2263/6366227
Isotype
IgG
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC882113-100 1x 100 µL
Involucrin (Squamous Cell Terminal Differentiation Marker) (IVRN/2113R), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
KN210211BN 1 Kit
12 Lipoxygenase (ALOX12) Human Gene Knockout Kit (CRISPR)
Sign In for Pricing
View Details 
![Peripherin (PRPH) Mouse Monoclonal Antibody [Clone ID: OTI2D5]](https://cdn.genprice.uk/products/937/68dd18b9061270361e907e73/imageurl/cf806182.webp)
CF806182 100 µg
Peripherin (PRPH) Mouse Monoclonal Antibody [Clone ID: OTI2D5]
Sign In for Pricing
View Details ![Elab Fluor® 488 Anti-Mouse CD103 Antibody[M290]](https://cdn.genprice.uk/products/763/68dd1498061270361e7ce3c0/imageurl/e-ab-f1090ul.webp)
E-AB-F1090UL-01 25 µg
Elab Fluor® 488 Anti-Mouse CD103 Antibody[M290]
Sign In for Pricing
View Details