Catenin beta Polyclonal Antibody
Product Specifications
Background
CTNNB1, also known as β-Catenin, is an evolutionarily conserved, multifunctional intracellular protein. CTNNB1 was originally identified in cell adherens junctions (Ajs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the Ajs, CTNNB1 is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. Deregulation of CTNNB1 activity is associated with multiple diseases including cancers. .
Abbreviation
Catenin beta
UniProt
P35222, Q02248, Q9WU82
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse β-catenin
Target
Beta catenin; Beta-catenin; Cadherin associated protein; Catenin (cadherin associated protein) ; beta 1;88kDa; Catenin beta 1; Catenin beta-1; CATNB; CHBCAT; CTNB1; CTNNB; CTNNB1; DKFZp686D02253; FLJ25606; FLJ37923; OTTHUMP00000162082; OTTHUMP00000165222; OTTHUMP00000165223; OTTHUMP00000209288; OTTHUMP00000209289
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC; IF
Field of Research
Cancer; Cardiovascular; Neuroscience; Signal Transduction; Stem Cells
Purification
Affinity purification
Concentration
0.97 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:300-1:1000; IF 1:200-1:800
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/5grkds
Product MSDS
https://789.bio/eb/4WnbbP
Calculated Molecular Weight
92kDa
Observed Molecular Weight
92kDa
Citation 01
https://academic.oup.com/bbb/article-abstract/85/11/2263/6366227
Isotype
IgG
Available Sizes
Curated Selection
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