Catenin beta Polyclonal Antibody

Product Specifications

Background

CTNNB1, also known as β-Catenin, is an evolutionarily conserved, multifunctional intracellular protein. CTNNB1 was originally identified in cell adherens junctions (Ajs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the Ajs, CTNNB1 is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. Deregulation of CTNNB1 activity is associated with multiple diseases including cancers. .

Abbreviation

Catenin beta

UniProt

P35222, Q02248, Q9WU82

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse β-catenin

Target

Beta catenin; Beta-catenin; Cadherin associated protein; Catenin (cadherin associated protein) ; beta 1;88kDa; Catenin beta 1; Catenin beta-1; CATNB; CHBCAT; CTNB1; CTNNB; CTNNB1; DKFZp686D02253; FLJ25606; FLJ37923; OTTHUMP00000162082; OTTHUMP00000165222; OTTHUMP00000165223; OTTHUMP00000209288; OTTHUMP00000209289

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC; IF

Field of Research

Cancer; Cardiovascular; Neuroscience; Signal Transduction; Stem Cells

Purification

Affinity purification

Concentration

0.97 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:300-1:1000; IF 1:200-1:800

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

92kDa

Observed Molecular Weight

92kDa

Citation 01

https://academic.oup.com/bbb/article-abstract/85/11/2263/6366227

Isotype

IgG

Available Sizes

Curated Selection

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BMP-15 (Bone Morphogenetic Protein 15) BioAssayTM ELISA Kit (Human) discontinued

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