Sparfloxacin
Sparfloxacin (CI-978) is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity[1].
Product Specifications
CAS Number
110871-86-8
Product Name Alternative
CI-978; AT-4140
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sparfloxacin.html
Purity
99.93
Solubility
0.1 M NaOH : 50 mg/mL (ultrasonic; adjust pH to 11 with NaOH) |DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL
Smiles
O=C(C1=CN(C2CC2)C3=C(C(N)=C(F)C(N4C[C@H](C)N[C@H](C)C4)=C3F)C1=O)O
Molecular Formula
C19H22F2N4O3
Molecular Weight
392.40
Precautions
H315, H319, H335
References & Citations
[1]Nakamura, S., et al., In vitro and in vivo antibacterial activities of AT-4140, a new broad-spectrum quinolone. Antimicrob Agents Chemother, 1989. 33 (8) : p. 1167-73.|[2]Pan, X.S. and L.M. Fisher, Targeting of DNA gyrase in Streptococcus pneumoniae by sparfloxacin: selective targeting of gyrase or topoisomerase IV by quinolones. Antimicrob Agents Chemother, 1997. 41 (2) : p. 471-4.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Quinolone
Available Sizes
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