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PPAR gamma Polyclonal Antibody

Product Specifications

Background

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

Abbreviation

PPAR gamma

UniProt

P37231

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

A synthetic peptide of human PPAR gamma

Target

CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARgamma; PPAR gamma; PPARG

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC; IF

Field of Research

Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Metabolism; Neuroscience; Stem Cells

Purification

Affinity purification

Concentration

1 mg/mL

Dilution

IHC 1:50-1:200; IF 1:50-1:20

Buffer

PBS with 0.01% thiomersal,50% glycerol, pH7.3.

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

21kDa/54kDa/57kDa

Observed Molecular Weight

57KDa

Isotype

IgG

Available Sizes

Curated Selection

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