INS Polyclonal Antibody
Product Specifications
Background
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.
Abbreviation
INS
UniProt
P01308
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant fusion protein of human INS (NP_000198.1) .
Target
IDDM; IDDM1; IDDM2; ILPR; IRDN; MODY10; INS; Insulin; insulin
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC; IF
Field of Research
Cancer; Cardiovascular; Metabolism; Neuroscience; Signal Transduction
Purification
Affinity purification
Concentration
1mg/mL
Dilution
IHC 1:50-1:200; IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/a5hpz5
Product MSDS
https://789.bio/eb/P4GWDC
Isotype
IgG
Available Sizes
Curated Selection
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