BBC3 Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.
Abbreviation
BBC3
UniProt
Q96PG8, Q9BXH1
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide of human BBC3 (NP_001120713.1) .
Target
BBC3; JFY-1; JFY1; PUMA
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IF
Purification
Affinity purification
Concentration
1mg/mL
Dilution
WB 1:500-1:2000; IF 1:50-1:100
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
10kDa/14kDa/20kDa/26kDa
Observed Molecular Weight
20kDa
Isotype
IgG
Available Sizes
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