NLRP12 Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.
Abbreviation
NLRP12
UniProt
P59046
Host
Rabbit
Reactivity
Rat
Immunogen
Recombinant fusion protein of human NLRP12 (NP_001264055.1) .
Target
NLRP12; CLR19.3; FCAS2; NALP12; PAN6; PYPAF7; RNO; RNO2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cell Biology; Signal Transduction
Purification
Affinity purification
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
31kDa/101kDa/107kDa/113kDa/114kDa/120kDa
Observed Molecular Weight
120kDa
Isotype
IgG
Available Sizes
Curated Selection
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