TIMP3 Polyclonal Antibody

Product Specifications

Background

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM) . Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.

Abbreviation

TIMP3

UniProt

P35625

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

A synthetic peptide of human TIMP3 (NP_000353.1) .

Target

TIMP3; HSMRK222; K222; K222TA2; SFD

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

Field of Research

Cancer; Cell Biology; Cardiovascular; Neuroscience; Signal Transduction

Purification

Affinity purification

Concentration

1mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

24kDa

Observed Molecular Weight

20kDa

Isotype

IgG

Available Sizes

Curated Selection

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