SIRT2 Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene.
Abbreviation
SIRT2
UniProt
Q8IXJ6
Host
Rabbit
Reactivity
Mouse; Rat
Immunogen
A synthetic peptide of human SIRT2
Target
SIRT2; SIR2; SIR2L; SIR2L2; sirtuin 2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Signal Transduction
Purification
Affinity purification
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
30kDa/35kDa/39kDa/41kDa/43kDa
Observed Molecular Weight
39kDa
Citation 01
https://www.mdpi.com/2076-3921/11/8/1611
Isotype
IgG
Available Sizes
Curated Selection
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