(KO Validated) Vimentin Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL) -derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.
Abbreviation
Vimentin
UniProt
P08670
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant fusion protein of human Vimentin (NP_003371.2) .
Target
CTRCT30; HEL113; Vimentin; VIM; vimentin
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC; IF
Field of Research
Cancer; Developmental biology; Neuroscience; Signaling transduction; Stem cells
Purification
Affinity purification
Concentration
1mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200; IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
53kDa
Observed Molecular Weight
57kDa
Isotype
IgG
Available Sizes
Curated Selection
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