SOCS3 Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN) -gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
Abbreviation
SOCS3
UniProt
O14543
Host
Rabbit
Reactivity
Mouse; Rat
Immunogen
A synthetic peptide of human SOCS3 (NP_003946.3) .
Target
SOCS3; ATOD4; CIS3; Cish3; SOCS-3; SSI-3; SSI3
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Metabolism; Immunology; Signal Transduction; Stem Cells
Purification
Affinity purification
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
24kDa
Observed Molecular Weight
33kDa
Citation 01
https://www.mdpi.com/1863624
Isotype
IgG
Available Sizes
Curated Selection
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