GLP1R Polyclonal Antibody
Product Specifications
Background
This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants.
Abbreviation
GLP1R
UniProt
P43220
Host
Rabbit
Reactivity
Mouse; Rat
Immunogen
Recombinant fusion protein of human GLP1R (NP_002053.3) .
Target
GLP1R; GLP-1; GLP-1-R; GLP-1R
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cardiovascular; Neuroscience
Purification
Affinity purification
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
53kDa
Observed Molecular Weight
53kDa
Isotype
IgG
Available Sizes
Curated Selection
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