YAP1 Polyclonal Antibody

Product Specifications

Background

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

Abbreviation

YAP1

UniProt

P46937

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant fusion protein of human YAP1 (NP_001123617.1) .

Target

COB1; YAP; YAP2; YAP65; YKI; YAP1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC; IF

Field of Research

Cancer; Epigenetics and Nuclear Signaling; Signal Transduction

Purification

Affinity purification

Concentration

1mg/mL

Dilution

IHC 1:50-1:100; IF 1:50-1:200

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Citation 01

https://www.nature.com/articles/s41590-022-01166-6

Isotype

IgG

Available Sizes

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