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CXCR4 Polyclonal Antibody

Product Specifications

Background

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Abbreviation

CXCR4

UniProt

P61073

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

A synthetic peptide of human CXCR4 (NP_003458.1) .

Target

CD184; D2S201E; FB22; HM89; HSY3RR; LAP-3; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM; WHIMS; CXCR4

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Cancer; Metabolism; Immunology; Microbiology; Neuroscience; Stem Cells

Purification

Affinity purification

Concentration

1mg/mL

Dilution

WB 1:500-1:1000

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

39kDa/40kDa

Observed Molecular Weight

36kDa/70kDa

Isotype

IgG

Available Sizes

Frequently Asked Questions

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